Prof. Dr. Stefan Gaubatz
Tel.: 0931 31-84138
Our main interest is transcriptional regulation of the mammalian cell cycle by the DREAM complex and Myb-MuvB (MMB). MMB together with the B-MYB transcription factor is a master activator of genes required for mitosis and cytokinesis.
We use biochemical and genetic methods to understand how DREAM, MuvB, B-MYB and its target genes contribute to normal proliferation, development and tumorigenesis.
Stopp S, Gründl M, Fackler M, Malkmus J, Leone M, Naumann R, Frantz S, Wolf E, von Eyss B, Engel FB, Gaubatz S (2017) Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci USA (doi: 10.1073/pnas.1703406114)