Lehrstuhl für Physiologische Chemie

Prof. Dr. Stefan Gaubatz

Physiological Chemistry
Biocenter
Am Hubland
97074 Würzburg

Tel.: 0931 31-84138
stefan.gaubatz@biozentrum.uni-wuerzburg.de

 

Our main interest is transcriptional regulation of the mammalian cell cycle by the DREAM complex and Myb-MuvB (MMB). MMB together with the B-MYB transcription factor is a master activator of genes required for mitosis and cytokinesis.

We use biochemical and genetic methods to understand how DREAM, MuvB, B-MYB and its target genes contribute to normal proliferation, development and tumorigenesis.

Latest:

Stopp S, Gründl M, Fackler M, Malkmus J, Leone M, Naumann R, Frantz S, Wolf E, von Eyss B, Engel FB, Gaubatz S Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci USA (in press)

Wolter P, Hanselmann S, Pattschull G, Schruf E, Gaubatz S (2017): Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapy. Oncotargetin press.    

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 > News

April 2017: Laura and Eva join the lab for their Bachelor thesis

June 2017: GAS2L3 paper accepted !

Bachelor- und Masterarbeiten ab sofort zu vergeben!

 

Kontakt Sekretariat
Physiologische Chemie
Biozentrum, Am Hubland
97074 Würzburg

Tel. +49 931 31-84148
Fax: +49 931 31-84150

Suche Ansprechpartner
Hubland Süd Hubland Nord Campus Dallenberg Fabrikschleichach Humangenetik Campus Medizin